The renin enzyme is made by special cells in the kidney. This enzyme can control blood pressure and various other physiological functions of the body. Not surprisingly, the function of the renin enzyme is closely related to the health of one's body.
The renin enzyme is made by special cells in the kidney. Renin together with the aldosterone hormone produced by the adrenal glands, and several other substances, play a role in regulating blood pressure by balancing the levels of sodium and potassium in the blood and the level of fluid in the body.
Relating to Kidney and Blood Pressure
The renin enzyme and the occurrence of high blood pressure caused by other health problems (secondary hypertension), are thought to have a close relationship with the possibility of kidney disease suffered. Because, a person suffering from kidney disease will lack blood flow, and cause excess renin production in the body. This high amount of renin triggers other substances in the body, especially angiotensin II, to influence the rise in a person's blood pressure.
For people with high blood pressure, your doctor may recommend checking renin and aldosterone levels to help determine the cause of your high blood pressure. The results of the examination can help guide the doctor in choosing the right treatment. The amount of renin in the body generally ranges from 0.2 - 3.3 (ng / mL / hour) or around 0.056 - 0.92 (ng / L / s).
Renin Enzyme Examination
Renin examination may need to be done to assess the function of the renin enzyme to work properly or not. Examination is done by taking blood samples to be examined in the laboratory.
Excessive amounts of the enzyme renin in the body are also closely linked to the possibility of a serious illness suffered by a person. Among them:
- Kidney illness.
- Blockage of arteries.
- Addison's disease.
- Cirrhosis.
- Excessive bleeding.
- Dangerous high blood pressure (malignant hypertension)
Meanwhile, low renin levels can indicate:
- Kidney illness.
- Hyperaldosterone (adrenal glands that produce too much aldosterone).
- Being in treatment (steroids or antidiuretic hormones).
- Conn's syndrome is commonly caused by a tumor in the adrenal gland.
In addition, the renin examination is also likely to be carried out together with the examination of aldosterone levels in the body. On examination results with a high amount of renin and low aldosterone, it is likely to make you have to immediately reduce salt intake to the body.
Conversely, for results that show low renin levels with high aldosterone levels, this might be a sign that the adrenal gland is no longer functioning properly. While the results in the form of renin and aldosterone levels are both high, this might be a sign of problems related to kidney health.
For patients with high blood pressure, renin examination is a way to find out the cause of high blood pressure suffered. Before conducting a renin examination, for 2 to 4 weeks it may be advisable to stop taking certain drugs that can affect the results of the renin test such as blood pressure drugs that are provoking urine production or diuretic groups (furosemide) and other groups such as beta blockers (bisoprolol, propranolol ) and ACE inhibitors (captopril), as well as medications containing the hormone estrogen.
Maintaining the function of the enzyme Renin
The function of the renin enzyme may not be as popular as other enzymes, but no less important role in regulating blood pressure. Beware of the disruption of the function of the renin enzyme that can possibly cause disease and also diseases that might affect the function of the renin enzyme for the body.
Live a healthy lifestyle by maintaining a balanced nutritional intake, multiply the consumption of water, get enough rest, limit consumption of caffeine from coffee, tea, and soda. Then avoid smoking, alcoholic drinks, drug consumption other than based on doctor's advice, stress and exercise regularly. It will maintain kidney health, so that the function of the renin enzyme goes well.
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